Mr. Spitzer, who resigned in a prostitution scandal in March 2008, is an adjunct professor in the political science department.
Ellis Simon, a spokesman for the Manhattan college, says the three-hour class is called “Law and Public Policy.”
The undergraduate course began meeting on Tuesday. It will meet once a week for 15 weeks.
Mr. Simon says Spitzer will earn around $4,500 for the fall term.
Since leaving public office, the Democrat has worked in his father’s real estate firm.
City College is part of the City University of New York system.