Dorothy Smith was last seen leaving her apartment at 334 East 108th Street around 12:30 p.m., according to the department.
She is described as being 5-foot-3-inches, 135 lbs, with white hair. She was last seen wearing a tan coat, blue pants and black boots.
Anyone with information is asked to call Crime stoppers at 1-800-577-TIPS (8477).
The public can also submit their tips by logging onto the Crime stoppers website or by texting their tips to 274637 (CRIMES) then enter TIP577.